Vitamin K 10mg tablet (Medione) 100s

₱71.00

Only 19 left in stock (can be backordered)

SKU: 11262018011243 Categories: ,

Description

Indications

 Listed in Dosage.

Dosage

 Adult : PO Vit K deficiency10 mg 6 hrly. Severe hypoprothrombinaemia 10 mg 3-4 times/day. IV Vit K Deficiency 0.03 mcg/kg/day. IM Haemorrhage or threatened haemorrhage during severe hypoprothrombinaemia 2.5-10 mg/day.

Dosage Details

 Intramuscular
Severe hypoprothrombinaemia

Adult: 2.5-10 mg daily.

Intravenous
Vitamin K deficiency

Adult: 0.03 mcg/kg/day.
Child: Infants: 1-5 mcg/kg/day.

Oral
Severe hypoprothrombinaemia

Adult: 10 mg 3-4 times daily.

Oral
Vitamin K deficiency

Adult: 10 mg every 6 hr.

Special Precautions

 Pregnancy. G6PD deficiency, vitamin E deficiency. Neonates, premature infants. Hepatic impairment. Monitor prothrombin time.

Adverse Drug Reactions

 Facial flushing, sweating, chest constriction/pain, dyspnoea, cyanosis, CV collapse. IM: Severe shock-like reactions, phlebitis, inj site reactions.
Potentially Fatal: Anaphylaxis.

Drug Interactions

 Decreases effects of oral anticoagulants.
 

Mechanism of Action

 Description: Menadione is a synthetic lipid-soluble vitamin K analogue. It is an essential cofactor in the hepatic synthesis of prothrombin (factor II) and other blood clotting factors (factors VII, IX, X and proteins C and S), and in the function of proteins important for bone development (e.g. osteocalcin).
Pharmacokinetics: 
Absorption: Requires bile for absorption from the GI tract.
Distribution: Accumulates in the liver; does not appear to cross the placenta.

Additional information

Weight 25.5 g
Dimensions 9.6 × 2.5 × 6.2 cm
location

davao, cdo, dipolog, butuan

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