TOBRAMYCIN + DEXAMETHASONE EYE DROPS (TOBRASON) 1s

165.50

Only 37 left in stock (can be backordered)

SKU: 09012020113222 Category:

Description

Indications

Ocular inflammation with suspected or confirmed bacterial infection.

Dosage

Adult : Ophth As susp containing tobramycin 0.3% and dexamethasone 0.1%: Instill 1-2 drops 4-6 hrly. May increase to 2 hrly during the initial 24-48 hr, reduce frequency gradually as improvement seen. As oint containing tobramycin 0.3% and dexamethasone 0.1%: Apply half an inch ≤3-4 times/day.

Dosage Details

Ophthalmic
Ocular inflammation with suspected or confirmed bacterial infection

Adult: As suspension containing tobramycin 0.3% and dexamethasone 0.1%: 1-2 drops instilled into the conjunctival sac(s) 4-6 hrly. Dosage may be increased to every 2 hrly during the initial 24-48 hr, decrease frequency gradually as improvement seen. As ointment containing tobramycin 0.3% and dexamethasone 0.1%: Apply about ½ inch of ointment into the conjunctival sac(s) up to 3-4 times daily.

Contraindications

Viral infections of corneal and conjunctiva (e.g. epithelial herpes simplex keratitis, vaccinia, varicella). Mycobacterial or fungal infection of the eye.

Special Precautions

Pregnancy and lactation. Avoid prolonged use, monitor intraocular pressure routinely. Safety and effectiveness in children <2 yr not established.

Adverse Drug Reactions

Hypersensitivity reactions, lid itching and swelling, conjunctival erythema, increase in intraocular pressure, glaucoma, optic nerve damage, posterior subcapsular cataract formation and delayed wound healing. Secondary infections especially after prolonged use.

Pregnancy Category (US FDA)

ROUTE(S) : Ophth
 
         

Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.

Mechanism of Action

Description: Tobramycin, an aminoglycoside antibiotic, has actions similar to that of gentamicin and is active against Staphylococci, Streptococci, Pseudomonas aeruginosaEscherichia coliKlebsiella pneumoniaeEnterobacter aerogenesProteus mirabilisMorganella morganii, most Proteus vulgarisstrains, Haemophilus influenzae and H. aegyptiusMoraxella lacunataAcinetobacter calcoaceticus and some Neisseria species. Dexamethasone, a synthetic fluorinated corticosteroid, has mainly glucocorticoid activity and suppresses inflammatory response.

Storage

Suspension: Store between 8-27°C (46-80°F); shake well before using. Ointment: Store between 8-27°C (46-80°F).

MIMS Class

Eye Antiseptics with Corticosteroids

Additional information

location

davao, cdo, dipolog, butuan