Description
Mechanism of Action
Menadione is a synthetic lipid-soluble vitamin K analogue. It is an essential cofactor in the hepatic synthesis of prothrombin (factor II) and other blood clotting factors (factors VII, IX, X and proteins C and S), and in the function of proteins important for bone development (e.g. osteocalcin).
Absorption: Requires bile for absorption from the GI tract.
Distribution: Accumulates in the liver; does not appear to cross the placenta.
MIMS Class
Haemostatics
ATC Classification
B02BA02 – menadione; Belongs to the class of vitamin K. Used in the treatment of hemorrhage.;
