Loratadine Tablet 10mg (LOALLER) 30s

101.00

Only 1 left in stock (can be backordered)

SKU: 06012015101644 Category:

Description

Mechanism of Action
Loratadine is a non-sedating antihistamine. It works by selectively binding to peripheral histamine H1-receptors on effector cells.
Onset: 1-3 hr.
Duration: >24 hr.
Absorption: Absorbed rapidly from the GI tract. Food delays time to peak plasma concentration and increases bioavailability. Time to peak plasma concentration: Approx 1 hr.
Distribution: Enters breast milk. Plasma protein binding: Approx 98%.
Metabolism: Undergoes extensive hepatic metabolism via CYP2D6 and CYP3A4 to desloratadine (major metabolite).
Excretion: Via urine and faeces (as metabolites). Mean elimination half-life: 8.4 hr (loratadine) and 28 hr (desloratadine).

MIMS Class
Antihistamines & Antiallergics 

ATC Classification
R06AX13 –  loratadine;  Belongs to the class of other antihistamines for systemic use

Additional information

location

davao, cdo, dipolog, butuan