Isosorbide Mononitrate 30mg (NITROFIX-30 *) 100s

752.00

Only 2 left in stock (can be backordered)

SKU: 08102012102240 Category:

Description

Mechanism of Action
Isosorbide mononitrate relaxes vascular smooth muscles by stimulating cyclic-GMP. It decreases left ventricular pressure (preload) and arterial resistance (afterload).
Onset: 20 min (oral as conventional tab).
Duration: 8-10 hr (oral as conventional tab).
Absorption: Readily absorbed from the GIT (oral); peak plasma concentrations after 1 hr.
Distribution: Widely distributed: Smooth muscle cells of the blood vessels.
Metabolism: Converted to inactive metabolites including isosorbide and isosorbide glucuronide.
Excretion: Via urine (2% as unchanged); 4-5 hr (elimination half-life).

MIMS Class
Anti-Anginal Drugs 

ATC Classification
C01DA14 –  isosorbide mononitrate;  Belongs to the class of organic nitrate vasodilators. Used in the treatment of cardiac disease.;  

Additional information

Weight 54.8 g
Dimensions 10 × 4.3 × 5.6 cm
location

davao, cdo, dipolog, butuan