Irbesartan Tablet 300mg (BELIZAR *(VE)) 28s

296.00

In stock (can be backordered)

SKU: 07172023110755 Category:

Description

Mechanism of Action
Irbesartan is an angiotensin II receptor antagonist. It blocks the vasoconstricting and aldosterone-secreting effects of angiotensin II by binding to AT1 receptors.
Onset: 1-2 hr.
Duration: >24 hr.
Absorption: Rapidly absorbed from the GI tract. Bioavailability: 60-80%. Time to peak plasma concentration: 1.5-2 hr.
Distribution: Volume of distribution: 53-93 L. Plasma protein binding: Approx 96%.
Metabolism: Undergoes hepatic metabolism via CYP2C9 isoenzyme to inactive metabolites.
Excretion: Via bile and urine (as unchanged drug and metabolites); urine (approx 20%, <2% as unchanged drug). Terminal elimination half-life: Approx 11-15 hr.

MIMS Class
Angiotensin II Antagonists 

ATC Classification
C09CA04 –  irbesartan;  Belongs to the class of angiotensin II antagonists. Used in the treatment of cardiovascular disease.;  

Additional information

Weight 32.4 g
Dimensions 9 × 2.7 × 7.4 cm
location

davao, cdo, dipolog, butuan