Fluconazole Capsule 150mg (FLUCONOBAS*) 5s

92.00

Out of stock

SKU: 04282021144357 Category:

Description

Mechanism of Action
Fluconazole decreases ergosterol synthesis by interfering with cytochrome P450 activity, thus inhibiting cell membrane formation of susceptible fungi including B dermatitidisCandida spp, C immitisC neoformansEpidermophyton spp, H capsulatum,Mycosporum spp, Trichophyton spp, thus leading to cell death.
Absorption: Well absorbed after oral admin; peak plasma concentrations after 1-2 hr (oral), may be increased with multiple dosing.
Distribution: Widely distributed. Protein-binding: 12%.
Excretion: Via urine (80% as unchanged, 11% as metabolites); 30 hr (elimination half-life); increased in renal impairment. Removed by dialysis.

MIMS Class
Antifungals 

ATC Classification
J02AC01 –  fluconazole;  Belongs to the class of triazole derivatives. Used in the systemic treatment of mycotic infections.;  
D01AC15 –  fluconazole;  Belongs to the class of imidazole and triazole derivatives. Used in the topical treatment of fungal infection.;  

Additional information

location

davao, cdo, dipolog, butuan