Description
Mechanism of Action
Finasteride is a competitive inhibitor of the enzyme 5-α reductase which converts testosterone to dihydrotestosterone (DHT), thus resulting in decreased serum levels of DHT.
Absorption: Absorbed from the GI tract (oral); peak plasma concentrations after 1-2 hr.
Distribution: Protein-binding: 90%.
Metabolism: Hepatic.
Excretion: Urine and faeces (as metabolites); <60 yr: 6 hr; >70 yr: 8 hr (elimination half-life).
MIMS Class
Other Dermatologicals / Drugs for Bladder & Prostate Disorders
ATC Classification
G04CB01 – finasteride; Belongs to the class of testosterone-5-alpha reductase inhibitors. Used in the treatment of benign prostatic hypertrophy.;
D11AX10 – finasteride; Belongs to the class of other dermatologicals.;
