Colchicine Tablet 500mcg (GOUTSAPH *) 100s

184.00

In stock (can be backordered)

SKU: 03102020033500 Category:

Description

Mechanism of Action
Colchicine, a phenanthrene derivative, exerts its effect by reducing the inflammatory response to the deposited urate crystals and also by diminishing phagocytosis in joints. It inhibits lactic acid production by leucocytes, thereby interrupting urate deposition and inflammatory response that sustains the acute gout attack.
Absorption: Peak plasma concentrations after 2 hr (oral).
Distribution: Leucocytes, kidneys, liver and spleen (high concentrations). Protein-binding: 10-31%.
Metabolism: Partially hepatic via deacetylation.
Excretion: Faeces and urine. Elimination half-life: 12-30 min (adult), 45 min (renal disease).

MIMS Class
Hyperuricemia & Gout Preparations 

ATC Classification
M04AC01 –  colchicine;  Belongs to the class of preparations with no effect on uric acid metabolism. Used in the treatment of gout.;  

Additional information

Weight 30.3 g
Dimensions 9.5 × 3 × 8 cm
location

davao, cdo, dipolog, butuan