Description
Mechanism of Action
Cinnarizine has calcium-channel blocking activity selective for arterial smooth muscle. It also has some antihistamine activity. Cinnarizine acts as a labyrinthine sedative. It also improves microcirculation by reducing ischaemia-induced blood viscosity.
Absorption: Absorbed from the GIT (oral); peak plasma concentrations after 2-4 hrs.
Excretion: Via faeces (as unchanged drug), via urine (as metabolites); 3-6 hrs (elimination half-life).
MIMS Class
Peripheral Vasodilators & Cerebral Activators / Antivertigo Drugs
ATC Classification
N07CA02 – cinnarizine; Belongs to the class of antivertigo preparations.;
