Description
Mechanism of Action
Bisacodyl acts mainly in the large intestine by increasng its motility to effect bowel evacuation.
Onset: 6-12 hr (oral). 15-60 min (rectal).
Absorption: Minimal from the GI tract (oral, as enteric-coated tablets/suppositories).
Metabolism: Converted to bis(p-hydroxyphenyl)pyridyl-2-methane by intestinal or bacterial enzymes.
Excretion: Faeces; urine (as glucuronide).
MIMS Class
Laxatives, Purgatives
ATC Classification
A06AG02 – bisacodyl; Belongs to the class of enemas. Used in the treatment of constipation.;
A06AB02 – bisacodyl; Belongs to the class of contact laxatives.;
