Description
Mechanism of Action
Salbutamol is a direct-acting sympathomimetic with β-adrenergic activity and selective action on β2 receptors, producing bronchodilating effects. It also decreases uterine contractility.
Onset: Inhalation: 5-15 min; oral: 30 min.
Duration: Inhalation: 3-6 hr; oral: 8 hr; modified-release preparation: 12 hr.
Absorption: Readily absorbed from the GI tract.
Metabolism: Hepatic and in the gut wall.
Excretion: Via the urine as metabolites and unchanged drug. Some excretion in the faeces.
MIMS Class
Drugs Acting on the Uterus / Antiasthmatic & COPD Preparations
ATC Classification
R03AC02 – salbutamol; Belongs to the class of adrenergic inhalants, selective beta-2-adrenoreceptor agonists. Used in the treatment of obstructive airway diseases.;
R03CC02 – salbutamol; Belongs to the class of adrenergics for systemic use, selective beta-2-adrenoreceptor agonists. Used in the treatment of obstructive airway diseases.;
