Description
Mechanism of Action
Phenylpropanolamine is an indirect acting sympathomimetic, often used orally as the HCl salt for nasal congestion. It has been withdrawn in several countries due to increased risk of haemorrhagic strokes.
Absorption: Readily and completely absorbed from GI tract. Time to peak plasma concentration: 1-2 hr.
Metabolism: Undergoes partial hepatic metabolism.
Excretion: Via urine 80-90% (unchanged). Half-life: Approx 3-5 hr.
MIMS Class
Cough & Cold Preparations
ATC Classification
R01BA01 – phenylpropanolamine; Belongs to the class of systemic sympathomimetic preparations used as nasal decongestants.;
