Description
Mechanism of Action
Hyoscine competitively blocks muscarinic receptors and has central and peripheral actions. It relaxes smooth muscle and reduces gastric and intestinal motility.
Onset: Oral, IM: 0.5-1 hr; IV: 10 min.
Duration: Oral, IM: 4-6 hr; IV: 2 hr.
Absorption: Tertiary salts: Readily absorbed. Quaternary salts: Poorly absorbed.
Distribution: Reversibly bound to plasma proteins.
Metabolism: Hepatic.
Excretion: Via urine (as metabolites); 4.8 hr (elimination half-life).
MIMS Class
Mydriatic Drugs / Muscle Relaxants / Antivertigo Drugs / Antispasmodics
