Ceftazidime Vial 1gm (MEDTAZIME) 1s

96.00

In stock (can be backordered)

SKU: 08302017035049 Category:

Description

Mechanism of Action
Ceftazidime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Absorption: Peak plasma concentrations after 1 hr (IM), 5 min (IV bolus).
Distribution: Widely distributed in body tissues and fluids; CSF (therapeutic concentrations when meninges are inflamed). Crosses the placenta and enters breast milk. Protein-binding: 10%
Excretion: Mainly by the kidneys via the urine by glomerular filtration (80-90% as unchanged drug within 24 hr); passively excreted in bile but only a small proportion is eliminated. Clearance enhanced in cystic fibrosis; 2 hr (elimination half-life), prolonged in neonates and renal impairment.

MIMS Class
Cephalosporins 

ATC Classification
J01DD02 –  ceftazidime;  Belongs to the class of third-generation cephalosporins. Used in the systemic treatment of infections.

Additional information

location

davao, cdo, dipolog, butuan