Description
Calcium carbonate can neutralise gastric acid rapidly and effectively. However, it may adversely activate Ca dependent processes, leading to secretion of gastric and hydrochloric acid. It can induce rebound acid secretion and, prolonged high doses may cause hypercalcemia, alkalosis and milk-alkali syndrome.
Absorption: Converted to calcium chloride by gastric acid. Some of the calcium is absorbed in the intestines. Calcium is absorbed in soluble, ionized form; solubility of calcium is increased in an acidic environment.
Distribution: Crosses placenta, enters breast milk.
Excretion: Mainly in the faeces as unabsorbed calcium; urine (20%).
MIMS Class
Calcium/with Vitamins / Antacids, Antireflux Agents & Antiulcerants / Electrolytes
ATC Classification
A02AC01 – calcium carbonate; Belongs to the class of calcium-containing antacids.;
A12AA04 – calcium carbonate; Belongs to the class of calcium-containing preparations. Used as dietary supplements.;
