Description
Mechanism of Action
Betamethasone is a corticosteroid with mainly glucocorticoid activity. It prevents and controls inflammation by controlling the rate of protein synthesis, depressing the migration of polymorphonuclear leukocytes and fibroblasts, and reversing capillary permeability and lysosomal stabilisation.
Absorption: Readily absorbed from the GI tract (oral).
Distribution: Distributed throughout body tissues; crosses the placenta and enters the breast milk.
Metabolism: Hepatic.
Excretion: Via urine (<5% as unchanged drug).
MIMS Class
Corticosteroid Hormones / Ear Corticosteroids / Eye Corticosteroids / Antiasthmatic & COPD Preparations / Topical Corticosteroids
ATC Classification
S01CB04 – betamethasone; Belongs to the class of corticosteroids/antiinfectives/mydriatics combinations. Used in the treatment of eye diseases.;
H02AB01 – betamethasone; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.;
D07AC01 – betamethasone; Belongs to the class of potent (group III) corticosteroids. Used in the treatment of dermatological diseases.;
C05AA05 – betamethasone; Belongs to the class of products containing corticosteroids for topical use. Used in the treatment of hemorrhoids and anal fissures.;
R01AD06 – betamethasone; Belongs to the class of topical corticosteroids used for prophylaxis and treatment of allergic rhinitis.;
A07EA04 – betamethasone; Belongs to the class of corticosteroids acting locally. Used in the treatment of intestinal inflammation.;
S03BA03 – betamethasone; Belongs to the class of corticosteroids used in ophthalmologic and otologic preparations.;
S02BA07 – betamethasone; Belongs to the class of corticosteroids used in the treatment of inflammation of the ear.;
R03BA04 – betamethasone; Belongs to the class of other inhalants used in the treatment of obstructive airway diseases, glucocorticoids.;
D07XC01 – betamethasone; Belongs to the class of potent (group III) corticosteroids in other combinations. Used in the treatment of dermatological diseases.;
S01BA06 – betamethasone; Belongs to the class of corticosteroids. Used in the treatment of inflammation of the eye.
